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Evolving treatment landscape in dMMR / MSI-H Colorectal cancer (CRC)

Agenda
12:05 – 12:35
New 1L CRC dMMR / MSI-H Landscape

Speaker: Prof. Thierry André, MD, Principal Investigator, Medical Oncologist, Sorbonne Université and Saint Antoine Hospital, Paris

CheckMate 8HW – presentation of key results
Practical aspects of treating dMMR / MSI-H CRC:

  • Diagnosis – how do we ensure dMMR/MSI-H patients are not missed out?
  • Subgroups of dMMR / MSI-H patients
  • Side effects of immunotherapy – how to prevent serious side effects?
  • Pseudoprogression – When does it come, and what should we do?
  • Oligometastatic progressive disease – What to do during / after therapy
  • Surgery of residual mass: Should it be done and when?

12:35 – 12:55
Discussion and questions from attendees
Moderator: Assoc. Prof. Jakob Eberhard, MD, Principal Investigator, Sr Consultant in Oncology, Skåne University Hospital, Lund

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